Our Award-Winning Inventions
(1) Minister of Education, Culture, Sports, Science and Technology Prize
Submitted Invention: Rapid, High-Precision Platelet Measurement Method (Patent Registration Number: 4659122)
This invention relates to a platelet measurement method for measuring platelets in blood. In general, fewer than 10,000 platelets per microliter of blood points to serious blood loss, necessitating transfusion. However, with conventional methods, accurately determining platelet numbers from samples with fewer platelets was problematic.
This invention uses a platelet measurement reagent containing Nile blue dye, whose counter ions are hydrogen sulfate, to stain the platelets. The stained platelets are then detected using scattered light and fluorescent light, enabling the platelets present in a sample, even in small numbers, to be counted quickly and with a high degree of precision. This allows decisions to be made as to whether a transfusion is necessary and if so, the appropriate transfusion amount. This approach reduces preventative overdosing of platelet transfusions, thereby lowering healthcare spending as well as the risk of secondary infectious disease stemming from transfusion.
This invention is used in one of Sysmex’s mainstay products, the XN-Series multiparameter automated hematology analyzer, and in Fluorocell PLT, the dedicated reagent for this analyzer. This invention also received the “Invention Implementation Achievement Award,” which is given to the representatives of companies recognized for their outstanding achievements in practical applications.
(2) The Encouragement Prize for Inventions
1) Submitted Invention: Analyzer for Managing Calibration Curves by Assigning IDs (Patent Number: 4969292)
This invention relates to an analyzer that assigns an ID to the calibration curve of a standard specimen to be measured in advance, and associates and manages the ID for the calibration curve of the test specimen and test results of a specimen. If test results are abnormal, this invention enables operators to revert to the calibration curve and investigate the cause of the abnormality, leading to enhanced test quality. Also, as both the calibration curve and ID are recorded, even if it is not possible to use the most recent calibration curve, a calibration curve employed in the past can be used again.
This invention is used with the HISCL-2000i, HISCL-5000 and HISCL-800 automated immunoassay systems.
2) Submitted Invention: Management Method for Predicting the Malfunction of Clinical Testing Instruments (Patent Number: 5735852)
This invention relates to a method for predicting malfunction by monitoring the operational information of pneumatic units used in clinical testing instruments. This invention predicts the time to repair or replace clinical testing instruments’ pneumatic units, facilitating preventive maintenance of instruments prior to malfunction. As a result, this invention helps to prevent clinical labs’ testing operations from being hindered by a sudden instrument malfunction.
This invention uses the SNCS (Sysmex Network Communication Systems)2 service.
3) Submitted Invention: Mutant Dockerin Polypeptide (Patent Number: 5307716)
This invention relates to mutant dockerin polypeptide that can be used to purify recombinant fusion proteins expressed when recombinant genes are introduced into the cells of plants and animals, yeast and bacteria. This invention enables a variety of recombinant fusion proteins to be purified in a short time without degrading activity.
This invention is used in the ProCube protein production service.